Pilot and Feasibility Grant Program


UCSF Diabetes and Endocrinology Research Center (DERC)
Pilot and Feasibility Awards

Project Award Amount up to $50,000


The DERC Pilot & Feasibility Program is funded through a Center grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to stimulate new directions in diabetes research regardless of a laboratory's traditional focus. Previous grantees that generate extramural grant applications within the initial funding period may apply competitively to the UCSF DERC Pilot & Feasibility Program for up to one additional year of bridge support which, provided funds are available, would maintain the research program until the completion of the extramural grant review process. Please be advised that the Fall 2010 cycle is funded with a one-time ARRA grant. There will be no opportunity for second year bridge funding for applications submitted in response to this RFA. Please ensure that your proposals represent one-year projects.

Pilot funding of up to $50,000 per application is available for a duration of 12 months from the time of award. Enhanced Pilot & Feasibility Awards of up to $100,000 for each of one or two years will be considered for highly exceptional proposals in clinical and translational research studies, innovative partnerships between clinical and basic research or in development of broadly useful and innovative technologies. Projects initially selected for Enhanced Pilot & Feasibility awards only will be offered after approval by NIDDK officials. Enhanced Pilot & Feasibility award holders also will be eligible to apply competitively for further bridge funding.

All grantees will be expected to participate in quarterly meetings with DERC faculty and other grantees to provide advice for the successful completion of the studies. The aim is to provide sufficient financial support and mentoring to allow the seed research to continue as an enduring, extramurally-funded program.

Any resulting publication must directly acknowledge the DERC grant award


P&F support is intended to allow the development of entirely new and exciting directions in diabetes research. Applications are encouraged from UCSF Faculty who are:

  • early stage investigators developing a diabetes research program.
  • established researchers not currently conducting studies directly related to diabetes but who desire to translate their non-diabetes research programs into a bold, new diabetes-related direction.
  • established researchers in diabetes who seek to develop entirely new research directions in diabetes.


Criteria for Review

The reviewers will examine the proposals for innovative research that will generate, within one year, seed data sufficient for future NIH grant applications in any aspect of clinical or basic research directly related to type 1 or type 2 diabetes. One year projects that create new knowledge or capabilities that can be used widely throughout the local and extramural diabetes research community also may be submitted in response to this RFA. Collaborative efforts with UCSF faculty currently engaged in diabetes-related research may better enable the successful completion of the approved research programs.

All applications are pre-reviewed by a board consisting of the Director of the UCSF DERC and the leaders of the four DERC research programs in Islet Biology, Obesity & Metabolism, Autoimmunity & Inflammation Program and Translation. Selected applications are sent out to 2-3 extramural reviewers. The UCSF board makes funding decisions based upon the reviews and portfolio balance. Evidence of required approvals must be completed before funding is released.

Apply online at  the UCSF resource and allocation program website


Emanuela (Emy) Volpe
CTSI-SOS Program Administrator
Ph.: 415-514-6208
E-mail: sos@ucsf.edu